The new FDA warning on NSAIDs seems to be don’t take too much too often but is vague on what that is. From FDA.gov:
Next time you reach into the medicine cabinet seeking relief for a headache, backache or arthritis, be aware of important safety information for non-steroidal anti-inflammatory drugs.
FDA is strengthening an existing warning in prescription drug labels and over-the-counter (OTC) Drug Facts labels to indicate that nonsteroidal anti-inflammatory drugs (NSAIDs) can increase the chance of a heart attack or stroke, either of which can lead to death. Those serious side effects can occur as early as the first few weeks of using an NSAID, and the risk might rise the longer people take NSAIDs. (Although aspirin is also an NSAID, this revised warning doesn’t apply to aspirin.)
Reading a warning like this makes us old guys with arthritis really interested in how much and how often. FDA doesn’t really say other than
FDA added a boxed warning to prescription drug labels for this risk in 2005. More recent data and information are prompting FDA to update NSAID labeling. Today we know that the risk of heart attack and stroke may occur early in treatment, even in the first weeks.
“There is no period of use shown to be without risk,” says Judy Racoosin, M.D., M.P.H., deputy director of FDA’s Division of Anesthesia, Analgesia, and Addiction Products.
As a regular user of ibuprofen and aspirin for arthritis and reminders that I wasn’t as indestructible as I thought I was a half-century ago, stuff like this is absolutely meaningless. (And, yes, my doc knows how much and frequency.)